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Semax
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Semax

$49.00 – $69.00 USD
Basic properties
IngredientsSemax acetate (SEMAX) — heptapeptide Met-Glu-His-Phe-Pro-Gly-Pro (MEHFPGP)
StorageBefore reconstitution (lyophilized powder): store frozen at -20°C for long-term storage; refrigeration at 2–8°C is also suitable for several months; protect from light and moisture. After reconstitution / nasal spray solution: store refrigerated (2–8°C) and typically use within 2–4 weeks. Avoid high temperatures, light, and repeated freeze-thaw cycles.
Specification table
SKU Content - Spec Pack Price Stock
XA5 5mg 10 vials $49.00 In stock
XA10 10mg 10 vials $69.00 In stock

Research use and intended-use limits

Research reagents are for laboratory and in-vitro research only. Not for human use.

Research reagents are not supplied as medicines and must not be used for diagnosis, treatment, prevention, clinical procedures or self-medication. Product information must not be used as administration or dosing guidance.

For accessories and consumables, follow their own specifications and documented intended use.

Description

Semax is a synthetic heptapeptide with the chemical sequence Met-Glu-His-Phe-Pro-Gly-Pro. It is an analog of the ACTH (4-10) fragment and was developed by the Russian Academy of Sciences. It is approved as a pharmaceutical in Russia, primarily for neuroprotection and cognitive enhancement. In other regions, it is mainly used as a research peptide or compounding preparation. Semax exhibits significant nootropic and neuroprotective effects, crosses the blood-brain barrier, and rapidly influences brain function. It is often used in combination with Selank. This content is intended for research and reference purposes only and should not be construed as medical advice.

Effects

Cognitive enhancement: Improves attention, memory, learning capacity, and information processing speed, with particularly pronounced effects under conditions of mental fatigue or stress. Neuroprotection: Promotes BDNF (brain-derived neurotrophic factor) expression, enhances neuroplasticity, and supports recovery from stroke, brain injury, or neurodegenerative disease. Anti-stress and mood regulation: Improves emotional stability, reduces anxiety, and supports stress management and mild depression. Other effects: May improve attention deficits (ADD/ADHD-like symptoms), enhance cerebral blood circulation, and support immune modulation and antioxidant activity. Characteristics: Relatively rapid onset, no notable sedation, and no disruption of the normal hormonal axis.

Usage

Common routes of administration: nasal spray/drops (most common and convenient, acting directly on the brain); subcutaneous injection (SC). Reference dosing (for reference only; follow physician's instructions): Nasal spray: 100–300 μg per dose, 1–3 times daily. Injection: 200–600 μg per dose, adjusted according to the specific protocol. Course of treatment: generally 10–14 days for cognitive enhancement; neurorehabilitation may require several weeks. Usage tips: Tilt the head slightly backward and spray gently when using the nasal spray; injections require aseptic technique. May be used alone or in combination with other neuropeptides such as Selank.