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IGF-1 LR3
Build muscle

IGF-1 LR3

$49.00 – $249.00 USD
Basic properties
IngredientsIGF-1 Long R3 (IGF-1 LR3) — 83 aa IGF-1 analog, Arg3 substitution + 13 aa N-terminal extension
StorageRefrigerate at low temperature (2-8°C). Avoid freezing and exposure to light.
Shelf life24 months
Specification table
SKU Content - Spec Pack Price Stock
IG01 100mcg 10 vials $49.00 In stock
IG1 1mg 10 vials $249.00 In stock

Research use and intended-use limits

Research reagents are for laboratory and in-vitro research only. Not for human use.

Research reagents are not supplied as medicines and must not be used for diagnosis, treatment, prevention, clinical procedures or self-medication. Product information must not be used as administration or dosing guidance.

For accessories and consumables, follow their own specifications and documented intended use.

Description

IGF-1 LR3 is an 83-amino acid synthetic analog of native IGF-1 featuring an arginine substitution at position 3 and a 13-amino acid N-terminal extension. These modifications reduce its binding affinity to IGF-binding proteins by over 100-fold, extending its half-life to approximately 20–30 hours compared to 12–15 minutes for unmodified IGF-1. This results in sustained IGF-1R activation and potent anabolic signaling via PI3K/Akt and MAPK/ERK pathways. Research shows it promotes skeletal muscle hypertrophy and hyperplasia, satellite cell proliferation, enhanced glucose uptake independent of insulin, accelerated wound healing, collagen deposition, and neuroprotective effects. While offering significant benefits for muscle growth, tissue regeneration, and body composition research, potential side effects include hypoglycemia, water retention, injection-site reactions, and theoretical risks of visceromegaly or tumor promotion with prolonged high-dose use. Cyclical administration with glucose monitoring is typically recommended in research settings.

Effects

Promotes muscle cell proliferation and differentiation; increases muscle mass and strength; accelerates post-exercise muscle recovery; reduces body fat percentage; supports bone health

Usage

Subcutaneous injection is recommended after exercise or before bedtime. The usual dose is 20-50 mcg per administration, once daily or every other day; after 4-6 weeks of continuous use, follow with a 2-4 week break.

Suitable for

Individuals training for fitness and muscle gain; patients with muscle wasting; individuals with slow metabolism; athletes in the rehabilitation phase